Atoms can neither be destroyed nor created during a simple chemical reaction. Therefore, in a chemical reaction
The sum of atoms before reaction = the sum of atoms after reaction

Balancing chemical equations may require some trial and error. There are some general rules that could be helpful, but they may not work all the time.
In this page, we will look at some examples of applying
Rule 2: Balancing chemical equations using the two’s and three’s technique.
Example:
Balance the equation
Fe + O2 → Fe2O3
Solution:
Step 1: On the left side of the equation there are 2 oxygen atoms and on the right side of the equation there are 3 oxygen atoms. To balance the oxygen atoms, multiply Fe2O3 by the coefficient of 2 and the O2 by the coefficient of 3
Fe + 3O2 → 2Fe2O3
Step 2: Balance the Fe by placing the coefficient of 4 in front of Fe
4Fe + 3O2 → 2Fe2O3
Step 3: Check that all the atoms balance and make sure that all coefficients are in the lowest-possible ratio.
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